WebBivalirudin, a direct thrombin inhibitor, is a treatment option for the management of heparin-induced thrombocytopenia (HIT) and other … WebNov 16, 2005 · In 29 (69%) patients, HIT was suspected because of a fall in platelet count and/or thrombosis in the setting of current or recent heparin therapy. HIT was confirmed …
Angiomax (bivalirudin) dosing, indications, interactions, adverse ...
WebApr 3, 2024 · LMWH has a decreased risk of heparin induced thrombocytopenia with thrombosis (HIT). ... Argatroban has traditionally been used more in the ICU (especially as a front-line agent for patients with HIT or suspected HIT). Bivalirudin has traditionally been used more in the cardiac catheterization laboratory. More recently, bivalirudin has been ... WebApr 6, 2024 · Due to the positive HIT screening test and delay in obtaining a follow-up serotonin release assay, it was decided to use bivalirudin for anticoagulation during cardiopulmonary bypass. Before cannulation, a bolus of 0.75 mg/kg was administered, and 5 minutes later the activated clotting time (ACT) test was performed. camping near hard rock casino tampa
The Role of Direct Oral Anticoagulants in the …
WebJun 19, 2024 · If initiating bivalirudin during PCI: Initial: 0.75 mg/kg bolus immediately prior to procedure, followed immediately by 1.75 mg/kg/hour for the duration of procedure. During the procedure, may determine ACT 5 minutes after bolus dose and administer an additional bolus of 0.3 mg/kg if necessary. WebThe major adverse effect of heparin is heparin-induced thrombocytopenia (HIT), a paradox in which an anticoagulant causes a severe procoagulant condition due to antibodies directed against the complex of heparin and … WebDec 15, 2024 · Treatment of Acute HIT/HITTS† IV. If bivalirudin is used for the treatment of HIT/HITTS, a continuous IV infusion of 0.15 mg/kg per hour adjusted to aPTT 1.5–2.5 times baseline has been used. No initial bolus dose is needed. Consider reduced infusion rate for renal or hepatic impairment. Special Populations Renal Impairment camping near happy jack a