Halothane, USP is an inhalation anesthetic chemically designated 2-bromo-2-chloro-1,1,1-trifluoroethane. The specific gravity is 1.872 to 1.877 at 20° C, and the boiling point (range) is 49° to 51° C, at 760 mm Hg. The vapor pressure is 243 mm Hg at 20° C. The blood/gas coefficient is 2.5 at 37° C, and the olive oil/water … See more When previous exposure to Halothane was followed by unexplained jaundice, consideration should be given to the use of other agents. Halothane, USP should be used in vaporizers … See more The following adverse reactions have been reported: Hepatic necrosis, cardiac arrest, hypotension, respiratory arrest, cardiac arrhythmias, … See more The uterine relaxation obtained with Halothane, unless carefully controlled, may fail to respond to ergot derivatives and oxytocic posterior pituitary extract (oxytocin injection). Halothane increases cerebrospinal fluid … See more Halothane, USP may be administered by the nonrebreathing technique, partial rebreathing, or closed technique. The induction dose varies … See more WebApr 10, 2024 · Doses and administration routes of the agents used in the mechanistic studies were selected by considering previous studies in our laboratory and the methods used in similar studies in the literature. ... (PBS) and paraformaldehyde in PBS (4%, pH 7.4) following anesthesia induced by halothane, and then their L4-L5 spinal cord segments …
Halothane: Uses, Interactions, Mechanism of Action …
WebHalothane is widely used for children, especially those with respiratory dysfunction because it tends to produce bronchial dilation. However, it is contraindicated for those with increased intracranial pressure (ICP). Adults. They should receive education about what will happen during administration of anesthesia. WebJul 8, 2024 · The US National Halothane Study found otherwise unexplainable fatal hepatic necrosis after halothane administration in 1 per 35,000 cases. The incidence after … cheapest jameson whiskey in uk
Beclomethasone (Inhalation Route) Proper Use - Mayo Clinic
WebApr 10, 2024 · Hepatotoxicity due to halothane administration is relatively common and is a major factor in its rapidly declining use. Type 1 hepatotoxicity has an incidence of 20% to 30%. A comprehensive report in 1969 demonstrated an incidence of type 2 hepatotoxicity (hepatitis) of 1 case per 6000 to 20000 cases, with fatal cases occurring approximately ... WebFeb 24, 2011 · Five Routes of Drug Administration. by admin on: February 24th, 2011 ... topical administration, (2) inhalation, (3) oral administration, (4) injection, and (5) … WebJun 19, 2024 · Although halothane has several drawbacks, the lack of flammability and general smoothness of administration led to rapid, widespread use, which only changed … cheapest jamaica all inclusive resorts